However, the co-administration of the BRAF inhibitor with the EGFR inhibitor cetuximab, tested in the BEACON trial, resulted in significantly longer overall survival and a higher response rate than standard therapy, with a safety toxicity profile establishing a new standard of care for patients with previously treated BRAF-V600E-mutant CRC [81]. The gene discussed is EGFR; the disease is colorectal carcinoma.