The Sall2−/− or Sal2−/+/p53−/− mice showed thymus T-cell lymphoma that metastasized to the liver, lung, kidney, marrow, peripheral blood, and central nervous system, while in most Sall2+/+/p53−/− mice, the lymphoma was limited to the thymus and adjacent organs such as the lung [25]. The gene discussed is SALL2; the disease is lymphoma.