MGMT and neoplasm: Despite dissection of the tumor after diagnosis and radiochemotherapy, patients have a dismal prognosis with, on average, 14.6 months (12.6 and 23.4 months in the O6-methylguanine-DNA methyltransferase (MGMT)-unmethylated and MGMT-methylated sub-group, respectively) [4] and a 2- and 5-year survival of 26.5% [2] and <10% [5], respectively.