CD4 and neoplasm: In addition, gene set enrichment analysis (GSEA) of 28 different immune specific cells across 19 TCGA tumors revealed high enrichment of activated CD8+ T cells, central memory CD4+ T cells, type 1 T helper cells, NK cells, CD56bright NK cells, myeloid-derived suppressor cells, plasmacytoid dendritic cells, immature dendritic cells, and monocytes in the majority of different tumor types (cutoff of NES > 0 and q-value < 0.1) (Figure 6).