RASSF1 and melanoma: More in detail, Koyanagi and colleagues identified a correlation between the number of melanoma markers (MART-1, GalNAc-T, and MAGE-A3 mRNAs), detected in the blood through quantitative real-time reverse transcription-PCR assay, the presence of circulating methylated RASSF1A and RAR-β2 genes (MSP detection), and patient outcome.