Interestingly, while use of anti-PD-L1 antibodies was found to indeed increase the anti-tumour effect of γδ T cells [41,194], this was not mediated by an increase in γδ T-cell cytotoxic activity, but rather by γδ T-cell-mediated ADCC induced by the tumour-targeting antibody [41]. Here, CD274 is linked to neoplasm.