CD8A and neoplasm: Furthermore, they showed that these γδ T cells effectively exercised cytolytic activities against ovarian cancer cells to a greater extent than patient-derived CD8+ T cells, and that patients who had more responsive γδT1 cells upon stimulation had smaller residual tumour burden and increased overall survival (OS), whereas the IFN-γ secretion capacity of αβ T cells was found to have no effect on patient survival [123].