The interaction of γδ T cells with suppressive polymorphonuclear cells (PMNs, also known as myeloid-derived suppressor cells or MDSCs) is multi-faceted; while γδT17 cells can recruit PMNs into the tumour [39], PMNs can in turn suppress cytotoxic γδT1 cells [40] and can provide a source of IL-10 and TGF-β to recruit Tregs, promoting immune suppression and tumour growth [182]. The gene discussed is TGFB1; the disease is neoplasm.