Susceptibility to Vγ9Vδ2 T-cell-mediated killing has also been reported to require tumour cell expression of stress-induced molecules such as NKG2D ligand, ULBP1 [150,160], ligands for DNAM-1 [141] or the cell adhesion molecule ICAM-1 [95]. The gene discussed is ICAM1; the disease is neoplasm.