Cooperation AML models of oncogenic NRAS has been also established with fusion genes such as NUP98 fusions (NUP98-NSD1, NUP98-JARID1A, and NUP98-DDX10) [43,153], KMT2A-AF9 [154], KMT2A-ENL [155], and RUNX1-RUNX1T1 [155]. The gene discussed is RUNX1; the disease is acute myeloid leukemia.