CD74 and breast cancer: Survival analysis using a multivariate Cox proportional hazards model on this breast cancer cohort (model: B_cell + CD8_Tcell + CD4_Tcell + Macrophage + Neutrophil + Dendritic + CD74), showed that from the six tested immune cell types and CD74 expression (dichotomized by median into low/high), only CD74 expression had independent prognostic value (Figure 4B; logrank p = 0.033).