FLT3 and acute myeloid leukemia: Aiming to identify vulnerable nodes in FLT3-ITD+ AML, so as to increase the therapeutic armamentarium for this disease, we performed high-throughput drug screening and evaluated the effect of a cancer drug library at a single dose (10 nM) on the viability of two FLT3-ITD+ AML cell lines, MV4-11 and MOLM13 (Figure 1A).