To investigate the relationship between BI-ALCL and cALCL and detect gene fusions, we applied an RNA sequencing (RNA-seq) approach, investigating 1385 genes recurrently translocated, mutated or deregulated in cancer, in 12 cALCLs, 10 BI-ALCLs and 2 ALK+ sALCLs. Here, ALK is linked to anaplastic large cell lymphoma.