Our data is strongly supported by published studies that have performed extensive immunohistochemical and fluorescence in situ hybridization to show that HER2 and PD-L1 are not only co-expressed but related to the gastric cancer stage and lymph node metastasis [36,37,38,39,40,41]. This evidence concerns the gene ERBB2 and metastatic malignant neoplasm in the lymph nodes.