However, since psoriasis patients show a lower incidence of non-melanoma skin cancer as well [40], despite the higher IL-17A presence in such a tumor microenvironment, probably other psoriasis-related factors are involved in sustaining the positive immune surveillance against skin tumor development, and Th-17/IL-17A presence could be a consequence instead of the leading cause of this immune surveillance. This evidence concerns the gene IL17A and skin neoplasm.