Furthermore, the three best biomarkers to separate early stage PDAC from IPMN were CA-125 (0.738 (0.643–0.833)), CA19-9 (0.702 (0.599–0.806)), and KRT19 (0.607 (0.499–0.715)). This evidence concerns the gene MUC16 and pancreatic intraductal papillary-mucinous neoplasm.