The first part of this study was devoted to the identification of RTK regulated by individual HDACs and, especially, HDAC class I. Computational analysis of RNA-sequencing data of 613 leukemia and NB patient samples and 88 cancer cell lines of the hematopoietic and neural origin, allowed us to identify NTRK1, FGFR3, AXL, KIT, PDGFR, ROR2, FLT3, RET, and INSR association with HDACs. This evidence concerns the gene INSR and neuroblastoma.