IL6 and infection: Furthermore, gene expression analysis for pro-inflammatory cytokines (IL1A, IL6, CXCL8), growth factors (TGFB1, PDGFC), transcription factors (NFKB1, TP53), and heat shock proteins (HSP90AA1, HSPA1A, HSPD1) as well as desmogleins (DSG1, DSG3) in keratinocytes and collagen (COL1A1, COL3A1) in fibroblasts was performed to evaluate cellular responses to healing progression (Table 1) under optimal conditions and infection with S. aureus as well as after priming with TNF-α/IFN-γ (chronic inflammatory milieu) or IL-4/IL-13 (anti-inflammatory conditions).