AIF1 and glaucoma: Once the existence of vitreous changes detected by OCT (VIT/RPE signal) was evidenced in glaucoma models, and the vitreous hyperreflective opacities were corroborated by histological studies as cell-like Iba-1+ hyalocytes with phagocytic activity, the vitreous signal was studied as an indirect representation of the immune population by analysing the size of the hyperreflective opacities [31,33].