ABCG2 and breast carcinoma: In another study, Wang et al. investigated in vitro the interaction between several antipsychotic drugs and MCF7/MX100 (resistant breast cancer) and Caco-2 (colon carcinoma) cell lines, both overexpressing the breast cancer resistance protein (BCRP), an energy-dependent transporter of the adenosine triphosphate-binding cassette (ABC) transporter family.