AURKB and Familial prostate cancer: Recently, Hongo et al., through in-silico drug screening, found that pimozide inhibits aurora B kinase (AURKB) and kinesin family member 20 A (KIF20A), involved in spindle formation and cytokinesis, in castration-resistant DU145CR prostate cancer cell line, and its combination with taxane cabazitaxel appears to have a synergistic effect in the same line in vivo and in vitro [57].