BIRC5 and cancer: In vitro, Sanomachi et al. supported that olanzapine specifically inhibits various cancer stem cell lines such as lung (A549) and pancreatic (PANC-1, PSN-1) in low concentrations, around 50μΜ, without affecting normal cells and increases the efficacy of several chemotherapeutic agents possibly by decreasing the expression of survivin in these cells [135].