EGFR is found to regulate NAFLD at various stages, starting from steatosis to NASH, and even with regard to fibrosis, while other RTKs discussed, such as AXL, FGFR4 and VEGFR, are also found to be effective in regulating different manifestations of NAFLD. The gene discussed is EGFR; the disease is metabolic dysfunction-associated steatotic liver disease.