In glioblastoma cells, Galangin (3,5,7-trihydroxyflavone), a natural flavonoid in plants, was observed to inhibit CD44 and EMT through vascular endothelial growth factor (VEGF) downregulation, suppressing the proliferation, invasion migration and angiogenesis of tumour cells [220]. This evidence concerns the gene VEGFA and glioblastoma.