NCOA4 and digestive system cancer: Several molecules, including tumor protein p53, perilipin2, retinoblastoma protein, nuclear factor NRF2, KH RNA binding domain containing signal transduction associated 1, cysteine dioxygenase type 1 (CDO1), metallothionein-1G, nuclear receptor coactivator 4(NCOA4), CDGSH iron-sulfur domain 1, heat shock protein family A (Hsp70) member 5, and acyl-CoA synthetase long chain family member 4, regulate ferroptosis in digestive system cancer [35].