Sun et al. used RNA-seq to analyze PLIN2 and differentially expressed genes modulated by PLIN2 in neoplastic tissues of both PLIN2 overexpression and knockdown groups in vivo, which indicated that overexpression and knockdown of PLIN2 augmented the proliferation and apoptosis of GC cell lines SGC7901 and MGC803, respectively, and PLIN2 was an indispensable gene and protein in the suppression of ferroptosis caused by abnormal lipomatabolism in GC [39]. Here, PLIN2 is linked to gastric cancer.