HSD11B1 and gestational diabetes: From the PPRs that may reflect the HSD11B1 activity, the cortisol/cortisone ratio was higher in the GDM+ group when compared with the GDM− group, but another PPRs that may reflect the HSD11B1 activity 7β-Hydroxy-DHEA/7-oxo-DHEA was lower in the GDM+ group (Table 9).