Given the critical roles of miRNAs in regulating type I IFN signaling, it is unknown whether the host cell uses these miRNAs to restart the IFN signaling pathways during FeHV-1 infection.To explore the vital role of miRNAs involved in the host resistance process to FeHV-1 infection, high-throughput sequencing of small RNAs after FeHV-1 infection was performed, showing that miR-26a was significantly upregulated at the time of infection [73]. The gene discussed is IFNA1; the disease is infection.