In addition, the current study also showed that IL-6 expression was positively correlated to the H/L ratio from the ileum of NI and SI chickens at 21 dpi; LITAF expression from the ileum of NI chickens was positively and negatively correlated to the H/L ratio at 7 and 21 dpi, respectively; a negative correlation between the H/L ratio and SOCS3 expression from the caecum of NI Chickens was found; and Muc2 and NF-κB expression from the caecum of NI chickens on day seven post-infection were negatively correlated to the H/L ratio. This evidence concerns the gene SOCS3 and infection.