EGFR and glioblastoma: By immunizing mice with purified recombinant hEGFR ectodomain (hEGFRec) from cultures of hEGFRec-overexpressed human glioblastoma, LN229, cells, we previously developed a novel anti-human EGFR (hEGFR) monoclonal antibody (mAb), namely EMab-134 [14].