PJ-34, a potent poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, may exert defense on intestinal epithelial cells (IECs) against invasive Salmonella infection by up-regulating IL-6 production through the ERK and NF-κB signal pathway [19]. This evidence concerns the gene PARP1 and Salmonella Infections.