SNAI1 and acute myeloid leukemia: Overexpression of SNAI1 is a pathologically relevant event in human acute myeloid leukemia (AML) that contributes to impaired differentiation and enhanced proliferation of immature myeloid cells, and ectopic expression of SNAI1 in hematopoietic cells predisposes to AML development, which is mediated by the interaction with the histone lysine-specific demethylase 1A KDM1A/LSD1 [51].