PTEN Q171R is curated in the Catalog of Somatic Mutations in Cancer (COSMIC; Genomic Mutation ID COSV64288519) database [15,16] and has been identified in two cases of breast cancer [17,18], one glioblastoma [19], one endometrial cancer [20], and one case of esophageal cancer [18], but has not been reported in colorectal cancer. The gene discussed is PTEN; the disease is colorectal cancer.