FPR1 and leukemia: Our data are in line with earlier works showing that HL60 leukemia cells exhibit an increase in intracellular Ca2+ entry in response to several differentiating inducers (i.e., the chemotactic peptide-FMLP and the mitogen Con-A [36], retinoic acid, 1 alpha, 25 dihydroxy vitamin D3 and dimethyl sulfoxide [37] and A23187 plus retinoic acid [38]).