We may assume, however, that HLA-A-Bw4 alleles, where A*23 and A*24 have the same peptide-binding motif different from other class I HLA alleles [49], contribute to later stages of AAA, expressed in its enlarged diameter, by presenting antigenic peptide to CD8+ T cells rather than by stimulating NK cells. Here, HLA-A is linked to triple-A syndrome.