Supplementation with propionate promotes the anti-inflammatory response of Treg cells to reduce local infiltration of immune cells, thereby reducing cardiac hypertrophy and fibrosis, susceptibility to cardiac arrhythmias, and atherosclerotic lesion burden and exhibits antihypertensive effects in angiotensin II (Ang II)-induced hypertension or atherosclerosis [46]. The gene discussed is AGT; the disease is cardiac hypertrophy.