CD8A and cancer: In addition, a recent study exploiting the fundamental mechanisms by which CD8+ T cells are regulated in response to pathogens and potentially cancer, demonstrated evidence for a critical role of lncRNA Morrbid in CD8+ T cell expansion, survival and effector function by modulating the expression of the pro-apoptotic factor Bcl-2-like protein 11 (Bcl2111) and the activity of the PI3K-AKT signaling pathway [47].