GADD45B and hepatocellular carcinoma: In contrast, lncRNA FOXF1 adjacent non-coding developmental regulatory RNA (FENDRR), by acting as a sponge to miR-423-5p in HCC cells, was able to upregulate growth arrest and DNA damage inducible beta (GADD45B), which in turn could inhibit Treg-mediated HCC immune escape [88].