GNAS and breast cancer: For example, expression of lncRNA GNAS antisense 1 (GNAS-AS1) in non-small cell lung cancer (NSCLC) and BC, enhances M2 macrophage polarization and consequently tumor immune-evasion through regulation of GNAS-AS1/MIR4319/NECAB3 and GNAS-AS1/miR-433-3p/GATA3 axes, respectively [56,57].