SFTPC and pulmonary fibrosis: Several transgenic strains mimic the characteristics of pulmonary fibrosis, such as human collagenase directed by the haptoglobin promoter [132], PDGF-B directed by the surfactant protein C (SP-C) promoter, human transforming growth factor-alpha (TGF-α) directed by the SP-C promoter [133], interleukin (IL)-11, and IL-13 directed by the bronchiolar exocrine/club cells 10-kDa (CC10) protein promoter [134,135].