Regulation of LncMALAT1 prevents cell migration and angiogenesis in retinal endothelial cells, alleviates neurodegeneration and inhibits monocyte chemotactic protein-1, and ameliorates inactivation of the master transcription factor, Nuclear factor erythroid 2-related factor, Nrf2, in rodent models of diabetic retinopathy [11,46,47]. This evidence concerns the gene CCL2 and diabetic retinopathy.