In this study, we investigated the prevalence of the SLC26A4 pathogenic variants in Tuvinian and Altaian patients where the causes of HL remained unknown after thorough testing for the GJB2 gene [45,48,49,51] and target screening for several mutations in other genes (MT-RNR1, MT-TS1, OTOF, RAI1) [46,47,50]. The gene discussed is MT-TS1; the disease is Hodgkins lymphoma.