Thus, although we cannot completely rule out any unrecognized SLC26A4 variants in other regions of the SLC26A4 sequence or large deletions, the SLC26A4 monoallelic patients in our samples were more likely to be coincidental carriers of a single SLC26A4 pathogenic variant, and other factors (other genes or environmental impacts) could have caused their HL. This evidence concerns the gene SLC26A4 and Hodgkins lymphoma.