LGALS3 and metastatic malignant neoplasm in the lymph nodes: Among the individual studies, it is worth noting Okada et al. study, in which decreased Gal-3 expression was associated with a poor prognosis also (RR = 3.831, 95% CI = 1.574–9.329, p = 0.0031), the degree of differentiation (p < 0.0001), lymph node metastasis (p = 0.0495), lymphatic invasion (p = 0.0086) and TNM stage (p = 0.0433) [71].