In particular, taking into account Holm–Bonferroni’s method for multiple comparisons, AD patients displayed significantly higher median neurogranin levels than the controls (p < 0.001) and patients with cerebrovascular diseases (p < 0.001), inflammatory CNS diseases (p = 0.002) and peripheral neuropathy (p < 0.001). The gene discussed is NRGN; the disease is Alzheimer disease.