TNF and nasal cavity polyp: In the context of the inflammatory component, Seong et al. (2002) demonstrated that the expression of MUC8 is increased in human nasal polyps compared with other mucins and that in the presence of inflammatory mediators such as TNFα and IL-1β, the mRNA of MUC8 is increased in nasal epithelial cells [32], as previously shown for normal human nasal epithelial cells by Yoon et al. (1999) [33].