In this study, we analyze the diagnostic accuracy of “FOB + Transferrin + Calprotectin + Lactoferrin® (Certest Biotec S.L, Zaragoza, Spain)”, a one-step combo card fecal test for the simultaneous semi-qualitative detection of haemoglobin, transferrin, calprotectin and lactoferrin in fecal samples of IBD patients. The gene discussed is LTF; the disease is inflammatory bowel disease.