Our study included age, sex, BMI, smoking and drinking habit, hypertension, hypercholesterolemia, duration of insulin-dependent diabetes mellitus (IDDM), use of ACE inhibitors and antihypertensive medicine, daily insulin dose, glycated hemoglobin (HbA1c) levels, total cholesterol, triglycerides, high-density lipoproteins (HDL), low-density lipoproteins (LDL), systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean blood pressure. This evidence concerns the gene INS and diabetes mellitus.