A retrospective cohort study of 610 patients showed a compound of age, history of coronary heart disease, CRP, aspartate aminotransferase, D-dimer, and neutrophil-to-lymphocyte ratio was able to form an acceptable ROC curve [43], and in a retrospective cohort study of 638 patients, CRP, neutrophil-to-lymphocyte ratio, and D-dimer were associated with adverse events, such as acute myocardial injury, respiratory failure, acute kidney injury, mechanical ventilation, intensive care unit admission, multiple organ dysfunction syndromes, and death [44]. This evidence concerns the gene CRP and respiratory failure.