The results of the CEUS LI-RADS category in the AFP-negative HCC group were 13 cases of LR-4 category, 38 cases of LR-5 category, and 10 cases of LR-M category, and 0, 3, and 35 cases of LR-4 category, LR-5 category, and LR-M category in the OM group respectively (Figure 1, Figure 2, Figure 3 and Figure 4), and there were no patients with LR-1, LR-2, or LR-3 in both groups. The gene discussed is AFP; the disease is hepatocellular carcinoma.