INSM1 and large cell neuroendocrine carcinoma: Another study evaluated INSM1 expression in 39 high grade NE carcinomas (4 in kidney, 28 in urinary bladder, and 7 in prostate); 31 small cell carcinomas (SmCCs), 6 large cell neuroendocrine carcinomas (LCNECs), 2 mixed SmCC-LCNECs) of the genitourinary tract and it compared it to SYN, CgA, and CD56.