Horachek et al. assessed the correlation between prognostic factors, overall survival and event-free survival and the serum levels of certain cytokines (soluble receptor α for IL-2, soluble receptor for IL-6, soluble receptor for TNF-α type I and soluble receptor for TNF-α type II) in adults diagnosed with B-cell precursor acute lymphoblastic leukemia [47]. The gene discussed is IL6; the disease is precursor B-cell acute lymphoblastic leukemia.