The mRNA levels of SREBP1, SREBP2, Bax, Bcl2, and caspase-3 were significantly lower, but mRNA levels of PPARα were significantly higher in the livers of both T2DM + BE (250 mg/kg) and T2DM (500 mg/kg)-treated rats when compared to T2DM rats (Figure 4A–D). The gene discussed is SREBF1; the disease is type 2 diabetes mellitus.