TNF and type 2 diabetes mellitus: In the same line, the observed increment in the levels of ROS, MDA, TNF-α, and IL-6, and the parallel reduction in the levels of the antioxidants (i.e., GSH and SOD) in the livers of T2DM-induced rats support the indispensable roles of oxidative stress and inflammation in mediating liver damage under HFD, and diabetic conditions, which support others [41,42,43,44,45].