The significance of closely related VEGF-EGFR intercorrelations and their activities were also described by Guo et al., who pointed out that the inhibition of this interaction may play a crucial role in some tumour proliferation signal pathway blockage [28], as the VEGFR-EGFR relation directly influences the inhibition of cell invasion and migration during the experimental conditions of wound healing. This evidence concerns the gene EGFR and neoplasm.