SOD1 and myeloid sarcoma: As shown in Figure 1A, when we investigated the ability of different immune-modulating treatments, as represented by teriflunomide, glatiramer acetate, IFN β 1b, dimethyl fumarate, cladribine, and fingolimod, to affect the SOD-1 intracellular content of T lymphocytes, we found that T cells from MS-RR individuals, undergoing fingolimod treatment, revealed a significantly lower SOD-1 content, as compared with T lymphocytes from MS-RR subjects receiving the other immune-modulating therapies.