CSF3 and anterior ischemic optic neuropathy: We previously demonstrated that systemic administration of granulocyte colony-stimulating factor (G-CSF), an old drug used to recruit the hematopoietic progenitors from bone marrow to peripheral blood, has neuroprotective effects not only in a rat model of anterior ischemic optic neuropathy (rAION) [17,18,19,20] but also in an optic nerve crush (ONC) model [21,22,23].