ANXA5 and adenocarcinoma: Collectively, the cell viability, Annexin V/PI detection, TUNEL assay, and Western blot findings indicate that pardaxin treatment significantly enhanced caspase-associated apoptosis in PA-1 and SKOV3 cells, which suggests that pardaxin induces cell death in epithelial teratocarcinoma and adenocarcinoma subtypes of OC.