Specifically, while smoking was associated with better sensory gating and PRT performance in the schizophrenia group, it was associated with impaired sensory gating and PRT performance in the bipolar disorder group (Figure 3A,B left panel), although the latter impairment was mitigated in individuals with bipolar disorder who were taking dopamine D2 receptor antagonists (Figure 3A,B right panel). Here, DRD2 is linked to bipolar disorder.