In contrast, pyroptosis rates among Casp-1++ were significantly increased in HD compared to BP patients (% granulocyte: 32.2 ± 18.6 vs. 14.4 ± 11.6, p = 0.002; % lymphocytes: 53.4 ± 15.0 vs. 19.5 ± 17.8, p = 0.001; Figure 2h). This evidence concerns the gene CASP1 and Huntington disease.