However, regarding the caspase-1 positivity of granulocytes and lymphocytes, it is clear that Casp-1++ cells are elevated in HD compared to BP (% granulocytes: 6.4 ± 5.9 vs. 3.4 ± 3.4, p = 0.054; % lymphocytes: 2.9 ± 2.7 vs. 1.2 ± 0.7, p = 0.011; Figure 1g) and prone to higher pyroptosis (% granulocytes: 35.8 ± 16.2 vs. 22.5 ± 14.2, p = 0.008; % lymphocytes: 32.9 ± 12.8 vs. 21.1 ± 16.5, p = 0.001; Figure 1h). Here, CASP1 is linked to Huntington disease.